Comments on: Pixantrone: Cardiac Issues Yes or No? http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/ Wed, 28 Oct 2009 10:20:17 -0600 http://wordpress.org/?v=2.8.2 hourly 1 By: Mark http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/comment-page-1/#comment-2167 Mark Sat, 18 Apr 2009 00:10:02 +0000 http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/#comment-2167 <p>When is ASCO?</p> When is ASCO?

]]> By: Pargoletto http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/comment-page-1/#comment-2161 Pargoletto Fri, 17 Apr 2009 06:40:15 +0000 http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/#comment-2161 <p>ciao Dan.. :-((</p> <p>io avere investito / ... preso tranvata... 1 one millions $$ in cioffy Cell... quanno pensi ke me ridai.... :-)) by salutame a Jonny.....</p> ciao Dan.. :-( (

io avere investito / … preso tranvata… 1 one millions $$ in cioffy Cell… quanno pensi ke me ridai…. :-) ) by salutame a Jonny…..

]]> By: Anonymous http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/comment-page-1/#comment-2160 Anonymous Fri, 17 Apr 2009 04:57:48 +0000 http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/#comment-2160 <p>Um, Dan Eramian doesn't know how to take his comp off ALLCAPS?</p> <p>Weird.</p> Um, Dan Eramian doesn’t know how to take his comp off ALLCAPS?

Weird.

]]> By: Mark http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/comment-page-1/#comment-2154 Mark Thu, 16 Apr 2009 17:10:14 +0000 http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/#comment-2154 <p>Dan Eramian- Did CTI receive the $3.5M from Spectrum that was reported to be received on April 15th? Thank you, M</p> Dan Eramian- Did CTI receive the $3.5M from Spectrum that was reported to be received on April 15th? Thank you, M

]]> By: Dan Eramian, CTI http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/comment-page-1/#comment-2153 Dan Eramian, CTI Thu, 16 Apr 2009 11:42:53 +0000 http://www.iguanabio.com/pixantrone-cardiac-issues-yes-or-no-2/#comment-2153 <p>1)SERIAL CARDIAC FUNCTION EVALUATION, A DIRECT MEASUREMENT OF THE DRUG'S POTENTIAL EFFECT ON THE HEART TISSUE WAS NO DIFFEREENT THAN STANDARD CHEMOTHERAPY. CARDIAC ADVERSE EVENTS IS A CLASSIFICATION THAT REFERS TO ANY CONDITION WHICH MAY LEAD TO A FAST HEART RATE, LOW BLOOD PRESSURE, ETC, WHETHER IT IS RELATED TO THE DRUG'S DIRECT DAMAGE TO THE HEART OR NOT. ONLY 1 CARDIAC ADVERSE EVENT WAS REPORTED IN THE TRIAL BELIEVED TO BE DUE TO THE EFFECT OF THE DRUG DESPITE THE FACT THAT ALL PATIENTS HAD AN AVERAGE OF MAXIMUM DOESES OF PRIOR ANTHRACYCLINE THERAPY---AN UNPRECENDENTED RESULT.</p> <p>2) THE NOVARTIS OPTION ON PIX REMIANS INTACT, IT IS ALSO TRUE THAT SINCE CTI RELEASED POSITIVE PHASE III RESULTS, OTHER COMPANIES HAVE APPROACHED THE COMPANY ABOUT A CO-PARTNERSHIP.</p> 1)SERIAL CARDIAC FUNCTION EVALUATION, A DIRECT MEASUREMENT OF THE DRUG’S POTENTIAL EFFECT ON THE HEART TISSUE WAS NO DIFFEREENT THAN STANDARD CHEMOTHERAPY. CARDIAC ADVERSE EVENTS IS A CLASSIFICATION THAT REFERS TO ANY CONDITION WHICH MAY LEAD TO A FAST HEART RATE, LOW BLOOD PRESSURE, ETC, WHETHER IT IS RELATED TO THE DRUG’S DIRECT DAMAGE TO THE HEART OR NOT. ONLY 1 CARDIAC ADVERSE EVENT WAS REPORTED IN THE TRIAL BELIEVED TO BE DUE TO THE EFFECT OF THE DRUG DESPITE THE FACT THAT ALL PATIENTS HAD AN AVERAGE OF MAXIMUM DOESES OF PRIOR ANTHRACYCLINE THERAPY—AN UNPRECENDENTED RESULT.

2) THE NOVARTIS OPTION ON PIX REMIANS INTACT, IT IS ALSO TRUE THAT SINCE CTI RELEASED POSITIVE PHASE III RESULTS, OTHER COMPANIES HAVE APPROACHED THE COMPANY ABOUT A CO-PARTNERSHIP.

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